RT-qPCR assay on the vitamin D receptor gene in type 2 diabetes and hypertension patients in Turkey.

Evaluation of the relationship between different polymorphisms of vitamin D receptor gene and renal diseases in patients with type 2 diabetes in Khuzestan province

The Association of Vitamin D Receptor Gene BsmI Polymorphism with Multiple Sclerosis in Iranian Patients

Background & Aims: 1,25-dihydroxyvitamin D3 (1,25 (OH)2 D3), the biologically active form of vitamin D, exerts an immunosuppressive effect through binding to its specific nuclear receptor. The present case-control study was done to examine the possible association of BsmI polymorphism in vitamin D receptor gene (VDR gene) with severity of multiple sclerosis (MS). Methods: 267 Iranian patients w...

اثر مکمل یاری کلسیتریول بر نمایه‌های متابولیک و فشارخون در بیماران دیابتی نوع2: کارآزمایی بالینی تصادفی شده دوسوکور

Background: According to previous studies, vitamin D has an inverse relation with some of the lipid and glucose profiles, and its deficiency is a risk factor for type 2 diabetes and cardiovascular disease. Therefore, the aim of this study was to evaluate the effect of vitamin D (calcitriol) on the blood glucose, lipid and hypertension profile in type 2 diabetic patients. Methods: In this Doubl...

Evaluation of relationship between BMI with vitamin D receptor gene expression and vitamin D levels of follicular fluid in overweight patients with polycystic ovary syndrome

Background Polycystic ovary syndrome (PCOS) is the most common endocrine disorder. The roles of vitamin D in the regulation of metabolic modulations specifically involving insulin action and reproduction processing are introduced. In addition, obesity appears to be closely associated with severity of PCOS. The aim of this study was to evaluate the effect of BMI on vitamin D levels in follicular...

Examination of the immunohistochemical localization and gene expression by RT-PCR of the oxytocin receptor in diabetic and non-diabetic mouse testis

Objective(s): The aim of this study was to determine Oxytocin receptor (OTR) gene expression and localization in diabetic and non-diabetic mouse testes by RT-PCR and immunohistochemistry, respectively. Materials and Methods: In this study, 18 male BALB/c mice (8–12 weeks old) were used and divided into three groups: diabetic, sham, and control. Streptozotocin (STZ) was applied to the diabetic g...